Our strain bank is developed through collaborations with leading academic institutions and research partners
worldwide, including those in Ireland, the United States, Japan, Canada, China, and
Indonesia.
worldwide, including those in Ireland, the United States, Japan, Canada, China, and
Indonesia.
We conducted whole-genome sequencing of our strains with the PacBio Sequel II and comprehensive experimental analyses. These studies identified strain-specific characteristics, underscoring their unique potential.
Our strains are deposited in the American Type Culture Collection (ATCC), Leibniz Institute DSMZ, and China General Microbiological Culture Collection (CGMCC).
Our probiotic strains have been rigorously evaluated for safety through genomic, laboratory, animal, and clinical studies.
Clinical Research, Scientific Validation.
We partner with leading academic institutions and renowned investigators to rigorously evaluate our purposefully designed probiotic formulations. Through the integration of human clinical trials, strain-specific research, and in vitro studies, we identify meaningful endpoints and uncover novel benefits for human health. By holding every formulation to the highest scientific standards, our work not only validates proven health outcomes but also contributes to advancing the broader fields of microbiome and probiotic science.
Advanced Equipment, Automation Technology
cGMP Standard, Intelligent Manufacturing
Fermentation
Large-scale intelligent fermentation system
Centrifugation
High-efficiency cell separation system
Emulsification
Multi-microencapsulation emulsification protection system
Drying
Vacuum freeze drying system
The Grisso® Team
The Grisso® Team
With decades of research experience and a strong record of peer-reviewed publications, our team ensures that every probiotic we create is firmly grounded in science. The experts behind our work—respected scholars and clinicians who lead cutting-edge laboratories and teach at leading universities—have collectively published over 1,200 scientific papers and garnered more than 80,000 citations in esteemed journals and reference works. Their combined knowledge and leadership provide the foundation for our probiotic research and product innovation, guided by the latest discoveries in human microbiome science.
Reynolds Paul Ross
Catherine Stanton
Deng Zixin
Grisso® Flagship Strains
Bifidobacterium animalis subsp. lactis BLa80
- Mediate sleep improvements through the gut-brain axis
- Support gut and mental health
- Immune system enhancement
- Improve bowel frequency and ease constipation
- Reduce serum cholesterol levels
- Inhibit the growth of Helicobacter pylori (H. pylori)
- Prevent allergy
Weizmannia coagulans BC99
- Decrease in anxiety (HAMA) and depression
- Enhance anti-inflammatory and neuroprotective activity
- Improve sleep quality and self-efficacy
- Alleviate chronic constipation
- Improve gastrointestinal symptoms
- Better gastric function
- Restoration of gut microbiota
Lacticaseibacillus rhamnosus LRa05
- Maintain a healthy vaginal flora
- Prevent urogenital infections
- Support overall reproductive health
- Regulate glycated hemoglobin and blood sugar
- Support immune and skin health
Lactiplantibacillus plantarum Lp05
- Gastrointestinal health
- Metabolic health
- Stomach inflammation improvement
- Oral health
- H. pylori suppression
- Reduce the risk of diarrhea linked to gut flora imbalance during treatment
Bifidobacterium breve BBr60
- Gastrointestinal Health
- Metabolic Health
- Immune Health
- Maternal & Child Health
- Emotional Health
Collaborative Clinical Institutes
Collaborative Clinical Institutes